Explores proximity-specific ribosome profiling and translational dynamics with high resolution, covering spatial regulation, cell architecture, ER's role, and advanced techniques.
Explores membrane protein quality control mechanisms at the ER, focusing on ERAD recognition, retrotranslocation, ubiquitination, and degradation of misfolded proteins.
Explores the evolution and function of protein-repair machineries, emphasizing the role of ATP-fueled unfolding machines in preventing protein aggregation and promoting proper folding.