DNA Methylation: Mechanisms and Applications

In course

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Description

This lecture covers the process of DNA methylation, focusing on the specific sequences that can be methylated and the enzymes involved. It explains how methylation affects DNA replication and gene expression, as well as its importance in genomic imprinting and X chromosome inactivation. The lecture also discusses the role of DNA methylation in severe combined immunodeficiency and how it can be detected using techniques like the HUMARA test.

Instructor

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Official source

https://mediaspace.epfl.ch/media/0_bmr25ftb

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Ontological neighbourhood

Biology

Genetics: Molecular genetics

Molecular biology: Chromosomes

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