Lecture

DNA Methylation: Mechanisms and Applications

Description

This lecture covers the process of DNA methylation, focusing on the specific sequences that can be methylated and the enzymes involved. It explains how methylation affects DNA replication and gene expression, as well as its importance in genomic imprinting and X chromosome inactivation. The lecture also discusses the role of DNA methylation in severe combined immunodeficiency and how it can be detected using techniques like the HUMARA test.

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