Lecture

Wittig Reaction: Stereoselective Synthesis

In course

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Description

This lecture covers the stereoselective synthesis using the Wittig reaction and its variants, including the formation of oxaphosphetane syn, coordination with potassium, and the equilibration process favoring trans betaine. It also discusses the use of KotBu for Li/K exchange and the Schlosser variant. The instructor presents examples of retrosynthetic analysis, asymmetric transformations, and selective diastereoselective reduction.

Instructors (2)

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Official source

https://mediaspace.epfl.ch/media/0_d6iuik4m

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