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Lecture
Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
This lecture covers the stereoselective synthesis using the Wittig reaction and its variants, including the formation of oxaphosphetane syn, coordination with potassium, and the equilibration process favoring trans betaine. It also discusses the use of KotBu for Li/K exchange and the Schlosser variant. The instructor presents examples of retrosynthetic analysis, asymmetric transformations, and selective diastereoselective reduction.