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This lecture covers the synthesis strategies and regioselectivity of bifunctionalized compounds, focusing on the selective enolization and electrophilic reactions of carbonyls. It also discusses the control of partners in the Eldolization process, the choice of disconnections, and the chiral auxiliaries used for selective enolization. The instructor explains the principles behind the strategies for bifunctionalized compounds, such as the Beyer-Villiger oxidation and coordination laws, emphasizing the importance of regioselectivity and stereoselectivity in organic synthesis.