The Chemistry of Poisonous Frogs

This lecture explores the chemistry behind the poison of various species of poisonous frogs, including the source of their toxins and how they avoid self-poisoning. It delves into the alkaloid compounds found in frogs, such as batrachotoxin and pumiliotoxins, and their effects on nerve and muscle cells. The lecture also discusses the protection mechanism of poisonous frogs against batrachotoxin through a specific amino acid mutation. Additionally, it covers the importance of organic chemistry in understanding everyday compounds and the potential medical applications of frog poisons. Various examples of poisonous alkaloids found in different frog species are presented, shedding light on the fascinating world of toxic amphibians.