Growth Hormone and Receptor: Mechanisms and Effects

This lecture covers different types of dwarfism, including laron dwarfism and pituitary dwarfism, as well as the mode of action of growth hormone and insulin-like growth factor 1. It explains the synthesis and secretion of growth hormone, the effects of growth hormone on bone and tissue growth, and the metabolic effects of growth hormone and IGF1. The lecture also discusses acromegaly, gigantism, and the JAK-STAT receptor pathway, which is involved in signaling from growth hormone and other cytokines to the nucleus for gene transcription.