Nuclear Receptors: Signalling and Health Implications

This lecture covers the activation and inhibition of nuclear receptors, focusing on the JAK-STAT pathway and its role in gene transcription. It also explores the applications of growth factors and cytokines in medicine, sports, and agriculture. The presentation delves into the structure and function of receptor tyrosine kinases, emphasizing their signaling mechanisms. Additionally, it discusses the impact of endocrine disruptors on the endocrine system, providing examples of compounds and their effects on health. The lecture concludes with insights into the detection of endocrine disruptors using fish models and the effects of common compounds on estrogen receptors.