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Explores Chemical Biology's interdisciplinary nature, enzyme inhibition, genetic methods, and metabolic regulation, highlighting its real-world relevance through recent Nobel Prize contributions.
Explores protein structure determination through X-ray crystallography, NMR spectroscopy, and Cryo-EM, covering crystallization, diffraction patterns, and atomic models.
Covers enzyme inhibition mechanisms, drug modes of action, targeted protein degradation using PROTACs, and the bump-hole method for protein-ligand engineering.
Delves into enzyme inhibition, reversible and irreversible binding, and covalent drugs, exploring drug modes of action and their impact on drug efficacy.
Explores kinase inhibitors, enzyme inhibition methods, transition state analog drugs, and the significance of covalent drugs in pharmaceutical research.
