This lecture covers compartmental models in computational neuroscience, focusing on active dendrites. It discusses the mathematical equations describing dendritic behavior, the spatial distribution of ion currents, and the software tools used for simulations. The lecture also explores a model by Hay et al. (2011) with 200 compartments, sodium and calcium currents, potassium currents, and an unspecific current. Additionally, it delves into experiments on active dendrites, including backpropagating action potentials and dendritic calcium spikes.