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Explores translation, mutations, ribosome function, protein folding, and degradation processes, emphasizing the genetic code's role in protein synthesis.
Explores proteinopathy mapping, connecting proteotoxicity to intrinsic functions of aggregation-prone proteins, with a focus on alpha-synuclein and Parkinson's Disease.
Delves into retooling the genetic code by expanding it beyond the standard amino acids, with a focus on eukaryotic mRNA translation and site-specific incorporation in fruit fly models.
Explores genetic code expansion through unnatural amino acids incorporation and biotechnological applications like mRNA display and SILAC-BONCAT techniques.