Lecture

Biochemical Equilibrium in Muscle Fibers

Description

This lecture discusses the conversion of G1P to G6P in muscle fibers under the action of phosphoglucomutase, leading to the production of lactic acid. The equilibrium constant is calculated, showing a favored direction. Enzymes affect kinetic factors but not thermodynamic factors. The lecture also covers the isomerization of G1P to G6P and F6P, involving concurrent reactions with different equilibrium constants. A system of equations is solved to determine the concentrations of G1P, G6P, and F6P at equilibrium, showcasing the evolution of two equilibriums simultaneously.

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