This lecture discusses the conversion of G1P to G6P in muscle fibers under the action of phosphoglucomutase, leading to the production of lactic acid. The equilibrium constant is calculated, showing a favored direction. Enzymes affect kinetic factors but not thermodynamic factors. The lecture also covers the isomerization of G1P to G6P and F6P, involving concurrent reactions with different equilibrium constants. A system of equations is solved to determine the concentrations of G1P, G6P, and F6P at equilibrium, showcasing the evolution of two equilibriums simultaneously.