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Lecture
Drug Targets: Adrenergic Signaling
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Pharmacokinetics: Drug Absorption and Distribution
Explores drug absorption, distribution, and clinical implications, focusing on salicylate poisoning and drug trapping in lysosomes.
Pharmacodynamics: Ligand-Receptor Interactions and Drug Effects
Explores ligand-receptor interactions, drug effects, modulation mechanisms, and factors influencing drug responses.
G Protein-Coupled Receptors: Signalling Diversity
Explores G protein-coupled receptors' signalling diversity, covering structure, activation, bias effects, and internalisation.
Receptors and Targeting
Explores receptors, ligands, and their role in signal transduction, including the activation of the immune system and the significance of multivalency in receptor-ligand interactions.
Selective Drug Targeting Mechanisms
Explores selective drug targeting mechanisms, resistance development, tuberculosis incidence, BCR-ABL mutations, tyrosine kinase inhibitors, drug toxicity, interactions, and toxicology studies.
Nuclear Receptors: Drug Targets
Explores nuclear receptors, their role in drug pharmacology, and physiological functions in adipose tissue and glucose homeostasis.
G Protein-Coupled Receptors: Structure and Signalling
Explores the structure, signalling, and drug targeting of G protein-coupled receptors, emphasizing their importance in pharmaceutical research.
G Protein-Coupled Receptors: Signalling Diversity and Complexity
Explores the diversity and complexity of G protein-coupled receptors, focusing on their signalling pathways, ligand effects, and cellular activity.
Pharmacodynamics: Ligand-Receptor Binding and Drug Effects
Explores ligand-receptor binding, drug effects, efficacy, potency, and biased agonism in pharmacodynamics.
Cellular Communication: Signaling Pathways and Receptors
Delves into the importance of intercellular communication and the diverse signaling pathways involved in cellular responses.