Preclinical Animal Models: Selection & Rationale

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Explores DNA-encoded libraries for drug discovery, covering synthesis techniques, pros and cons, and diverse DEL methods.

Pharmacological Targets and Interventions

Explores targets for drug action and the design of specific inhibitors.

Protein-Ligand Interactions: Importance and Affinity

Explores the importance of protein-ligand interactions, focusing on binding affinities and energetic landscapes, with implications for drug development and specificity.

Total Synthesis: Strategies and Impact

Explores total synthesis of natural products, strategies, impact on science and society, drug development, and biological studies.

Pharmacokinetics: Drug Absorption and Distribution

Explores drug absorption, distribution, and clinical implications, focusing on salicylate poisoning and drug trapping in lysosomes.

Peptide Therapeutics

Explores the development and advantages of peptide therapeutics, including conversion into peptidomimetics and solid phase peptide synthesis.

Pharmacodynamics and Drug Targets

Explores pharmacodynamics, drug targets, the renin-angiotensin system, ACE inhibitors, diuretics, and exam questions.

Drug-Induced Liver Injury (DILI): Mechanisms and Mitigation

Delves into Drug-Induced Liver Injury (DILI) mechanisms, metabolism, and mitigation strategies in drug development.

Platinum Drugs: Chemistry and Cancer Treatment

Covers the role of platinum-based drugs in cancer treatment and their chemical mechanisms.

Fragment-Based Drug Discovery: Concepts & Technologies

Covers the concepts and technologies of fragment-based drug discovery, hit identification methods, and its application in target-based drug discovery.