This lecture explores the design, fabrication, and functionality of soft bio-integrated and bio-mimetic electronics for mobile health and human-centered robotics. It discusses the challenges of merging humans with machines and electronics, focusing on the development of soft electronics based on inorganic functional materials. The talk covers the invention of electronic tattoos (e-tattoos) for physiological sensing and prosthesis/robot control, as well as the engineering of e-skins with high pressure sensitivity. Future opportunities and challenges in the field of soft bioelectronics are also discussed.