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This lecture covers the taxonomy of RNA viruses, including single-strand positive, single-strand negative, and double-strand viruses. It also explains the biosynthesis of DNA and RNA viruses, detailing the special features of different virus families. The lecture further explores virus strategies for generating messenger RNA and the transformation of viral genetic information into proteins. Additionally, it delves into microbial taxonomy, infection, colonization, and constitutive defense mechanisms, as well as bacterial classification and taxonomy. The lecture concludes with a focus on Mycoplasma characteristics, such as their small size, pleomorphism, lack of a rigid cell wall, and resistance to penicillin.