Lecture

Catalytic asymmetric reactions

Description

This lecture covers the principles of catalytic asymmetric reactions in organic chemistry, focusing on topics such as asymmetric induction, kinetic resolution of chiral compounds, and the activation of carbonyls and imines. The instructor discusses key concepts like the modes of asymmetric induction, catalyst release, and bond formation, using examples such as the Aldol reaction and kinetic resolution. Various catalysts, including chiral boron and binol-based catalysts, are explored for their role in achieving high enantioselectivity. The lecture also delves into non-linear effects and the reservoir effect observed in catalytic reactions, providing insights into the complexities of asymmetric catalysis.

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