Drug-Induced Liver Injury (DILI): Mechanisms and Mitigation

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Synthetic Biology: Therapeutic Advancement

Introduces synthetic biology for disease treatment, covering RNA therapeutics, drug discovery, and gene circuits.

Deep Generative Models in Drug Discovery

Explores the application of deep generative models in drug discovery, focusing on designing small molecules and optimizing molecular structures.

Chemical Biology Toolsets: Enzyme Inhibition and Metabolic Signaling

Explores enzyme inhibition, metabolic signaling, glycolysis, and isotopic tracing in central carbon metabolism.

Drug Targets: Adrenergic Signaling

Explores drug targets and adrenergic signaling, covering receptors, enzymes, and transporter proteins.

Regulation Mechanisms Overview

Covers phosphorylation, ubiquitinylation, methylation, and more in biological regulation.

Liver Detoxification: Bile Acids, Cholesterol, and Xenobiotics

Explores liver metabolism of bile acids, cholesterol, and xenobiotics, emphasizing detoxification processes and lipid transport.

Neuroepigenetics: Chromatin Structure and Regulation

Explores neuroepigenetics, focusing on chromatin structure, regulation, and epigenetic inheritance in neurodevelopment.

Drug Targets: Nuclear Receptors

Explores drug targets, particularly nuclear receptors like PPARy and pregnane X receptor, and their impact on endocrine signaling and drug pharmacokinetics.

Drug Targets: ligand-gated ion channels and kinase-linked receptors

Explores drug targets in ligand-gated ion channels and kinase-linked receptors, focusing on GABAA receptors, benzodiazepines, and insulin therapy.

Neuroepigenetics: Chromatin Regulation and Memory Formation

Delves into chromatin regulation's role in memory formation, genetic and epigenetic influences on learning, and the potential of HDAC inhibitors as cognitive enhancers.