Explores the applications of CRISPR-Cas in genome editing, focusing on engineering bacterial genomes, curing genetic diseases, guide RNA simplicity, Cas9 specificity, DNA damage mechanisms, and base editing.
Covers the basics of polymer biophysics, including DNA conformation modeling and the Boltzmann principle, emphasizing the exponential decay of correlations between segments.
Explores RNA switches' design and applications in synthetic biology, focusing on nature-inspired regulatory RNA principles for creating new biomolecular components and networks.
