Covers sustaining proliferation in cancer cells, growth factors, receptor tyrosine kinases, signal transduction, viral oncogenes, and therapeutic opportunities.
Covers the design and analysis of inhibitors for next-generation covalent drugs, focusing on target engagement and the importance of cysteine targeting.
Explores the importance of protein-ligand interactions, focusing on binding affinities and energetic landscapes, with implications for drug development and specificity.
Covers proteomic applications in neuroscience, focusing on targeted analysis of cortical neurons and their developmental interactions with striatal neurons.
Delves into enzyme inhibition, reversible and irreversible binding, and covalent drugs, exploring drug modes of action and their impact on drug efficacy.
