Explores kinase inhibitors, enzyme inhibition methods, transition state analog drugs, and the significance of covalent drugs in pharmaceutical research.
Covers enzyme inhibition mechanisms, drug modes of action, targeted protein degradation using PROTACs, and the bump-hole method for protein-ligand engineering.
Explores enzyme inhibition mechanisms, including competitive, uncompetitive, and mixed inhibition, as well as autocatalysis and their impact on enzyme kinetics.