Protein Phosphorylation: Mechanisms and Regulation

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Cellular Communication: Signaling Pathways and Receptors

Delves into the importance of intercellular communication and the diverse signaling pathways involved in cellular responses.

Cell Membrane Receptors: General Principles

Explains cell membrane receptors, signal transduction, and second messengers.

SEGREGATION of KINETIC REACTIVITY & BINDING AFFINITY

The paper focuses on the importance of reversible interactions to potency and mechanisms of drug resistance.

Protein Maturation: Post-Translational Modifications

Covers the maturation of proteins and the role of post-translational modifications in their functionality and regulation.

GPCRs: Molecular Endocrinology

Explores the structure and activation of 7TM receptors and the downstream effects of CAMP and protein kinase A.

DNA Damage Checkpoint

Explores the DNA damage checkpoint, cell cycle regulation, repair mechanisms, and key proteins involved.

Kinase Inhibitors: Types and Mechanisms

Explores kinase inhibitors, their types, mechanisms, and experimental evaluation, emphasizing the significance of covalent drugs in modern pharmaceutical research.

Altered Pathways in Cancer: Signaling Cascades and Mutations

Explores cancer pathways, major signaling cascades, and mutations in RAS and BRAF genes.

Protein Structure & Modifications

Explores protein structure analysis, folding, modifications, and their impact on diseases and protein activity regulation.

Bacterial Signalling: Two-component Systems

Explores bacterial two-component signalling systems, gene regulation, chemotaxis, and flagellar rotation in E. coli.