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This lecture covers the dissociation of molecules to determine if they are acids or bases, based on the presence of ionizable hydrogen atoms and electronnegativity. It also explains how to calculate the pH of solutions, the concept of acid strength, and the use of buffer solutions to maintain pH levels. Examples include the dissociation of weak acids like acetic acid and the effect of common ions on the equilibrium. The lecture also discusses the pH calculation for strong and weak acids and bases, as well as the significance of buffer solutions in maintaining stable pH levels.