Person
Michael Stefan Daniel Liebling
Related publications (21)
Temporal Super-Resolution Microscopy Using a Hue-Encoded Shutter
Sylvain Calinon, Michael Stefan Daniel Liebling, Emmanuel Pignat, Christian Jaques
Limited time-resolution in microscopy is an obstacle to many biological studies.
Despite recent advances in hardware, digital cameras have limited operation modes that constrain
frame-rate, integration time, and color sensing patterns. In this paper, we pr ...
2019Semi-Blind Spatially-Variant Deconvolution in Optical Microscopy with Local Point Spread Function Estimation By Use Of Convolutional Neural Networks
Michael Stefan Daniel Liebling, Adrian Shajkofci
We present a semi-blind, spatially-variant deconvolution technique aimed at optical microscopy that combines a local estimation step of the point spread function (PSF) and deconvolution using a spatially variant, regularized Richardson-Lucy algorithm. To f ...
2018Semi-blind spatially-variant deconvolution in optical microscopy with local Point Spread Function estimation by use of Convolutional Neural Networks
Michael Stefan Daniel Liebling, Adrian Shajkofci
We present a semi-blind, spatially-variant deconvolution technique aimed at optical microscopy that combines a local estimation step of the point spread function (PSF) and deconvolution using a spatially variant, regularized Richardson-Lucy algorithm. To f ...
Idiap2018A Point-Spread-Function-Aware Filtered Backprojection Algorithm for Focal-Plane-Scanning Optical Projection Tomography
Michael Stefan Daniel Liebling
Traditional optical projection tomography requires the use of low numerical aperture objectives in order to achieve a large depth of field and approximate parallel projection geometry. However, low NA objectives suffer from poor resolution, resulting in bl ...
2016Simultaneous temporal superresolution and denoising for cardiac fluorescence microscopy
Michael Stefan Daniel Liebling
Due to low light emission of fluorescent samples, live fluorescence microscopy imposes a tradeoff between spatiotemporal resolution and signal-to-noise ratio. This can result in images and videos containing motion blur or Poisson-type shot noise, depending ...
2016Intensity-Based Point-Spread-Function-Aware Registration for Multi-View Applications in Optical Microscopy
Michael Stefan Daniel Liebling
We present an algorithm to spatially register two volumetric datasets related via a rigid-body transform and degraded by an anisotropic point-spread-function (PSF). Registration is necessary, for example, when fusing data in multi-view microscopy. Automati ...
2015Estimation of Divergence-Free 3D Cardiac Blood Flow in a Zebrafish Larva Using Multi-View Microscopy
Michael Stefan Daniel Liebling
Conventional fluid flow estimation methods for in vivo optical microscopy are limited to two-dimensions and are only able to estimate the components of flow parallel to the imaging plane. This limits the study of flow in more intricate biological structure ...
2015