Stewart Cole

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Related publications (489)

A protein linkage map of the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis

Stewart Cole

Tuberculosis is a chronic infectious disease caused by bacteria of the Mycobacterium tuberculosis complex. One of the major contributors to virulence and intercellular spread of M. tuberculosis is the ESAT-6 secretion system 1 (ESX-1) that has been lost by ...

2007

Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues

Stewart Cole

We recently reported that 3,3-dimethyl-3H-benzofuro[3,2,f][1]-benzopyran and its hydrogenated analogue are selective in vitro inhibitors of mycobacterial growth. However, their lack of in vivo activity on a murine model of Mycobacterium tuberculosis infect ...

2007

Moments of the electron energy spectrum and partial branching fraction of B→Xceν decays at the Belle detector

Olivier Schneider, Stewart Cole, Chao Wang, Tagir Aushev, Lei Zhang, Sun Hee Kim, Jing Li

We report a measurement of the inclusive electron energy spectrum for charmed semileptonic decays of B mesons in a 140fb-1 data sample collected at the Υ(4S) resonance with the Belle detector at the KEKB asymmetric energy e+e- collider. We determine the fi ...

2007

, , , , , ,

The inclusive production of Ds, D0, and J/ψ mesons is studied using a 1.86fb-1 data sample collected on the Υ(5S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. The number of bb̄ events in this Υ(5S) data sample is determine ...

2007

A point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra

Stewart Cole

Similarities between Mycobacterium tuberculosis phoP-phoR mutants and the attenuated laboratory strain M. tuberculosis H37Ra in terms of morphological and cytochemical properties, lipid content, gene expression and virulence attenuation prompted us to anal ...

2007

Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis

Stewart Cole, Petra Tafelmeyer

The role of biofilms in the pathogenesis of mycobacterial diseases remains largely unknown. Mycobacterium ulcerans, the etiological agent of Buruli ulcer, a disfiguring disease in humans, adopts a biofilm-like structure in vitro and in vivo, displaying an ...

2007

Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva

Stewart Cole

BACKGROUND: Buruli ulcer is a severe human skin disease caused by Mycobacterium ulcerans. This disease is primarily diagnosed in West Africa with increasing incidence. Antimycobacterial drug therapy is relatively effective during the preulcerative stage of ...

2007

Study of the charmed baryonic decays B̄0→Σc++p̄π- and B̄0→Σc0p̄π+

Olivier Schneider, Stewart Cole, Mingkui Wang, Chao Wang, Tagir Aushev, Lei Zhang, Sun Hee Kim, Jing Li

We study the three-body charmed baryonic decays B̄0→Σ c++p̄π- and B̄0→Σc0p̄π+ in the four-body final state B̄0→Λc+p̄π+π-, using a data sample of 357fb-1 accumulated at the Υ(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. ...

2007

Measurements of branching fractions and q2 distributions for B → π ℓ ν and B → ρ ℓ ν decays with B → D(*) ℓ ν decay tagging

Olivier Schneider, Aurelio Bay, Stewart Cole, Mingkui Wang, Chao Wang, Tagir Aushev, Lei Zhang, Vladislav Balagura, Jing Li

We report measurements of the charmless semileptonic decays B0 → π- / ρ- ℓ+ ν and B+ → π0 / ρ0 ℓ+ ν, based on a sample of 2.75 × 108B over(B, ̄) events collected at the Υ{hooked} (4 S) resonance with the Belle detector at the KEKB e+ e- asymmetric collider ...

2007

Search for b→h(*)νν̄ decays at belle

Olivier Schneider, Aurelio Bay, Stewart Cole, Mingkui Wang, Chao Wang, Tagir Aushev, Vladislav Balagura

We present a search for the rare decays B→h()νν̄, where h() stands for a light meson. A data sample of 535×106 BB̄ pairs collected with the Belle detector at the KEKB e+e- collider is used. Signal candidates are required to have an accompanying B meson f ...

2007

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