Publications by Mahmut Selman Sakar

Technology Roadmap of Micro/Nanorobots

American Chemical Society (ACS)2025

An acoustic levitation platform for high-content histological analysis of 3D tissue culture

Mahmut Selman Sakar, Emilie Vuille-Dit-Bille

Miniaturized three-dimensional (3D) cell culture systems, in particular organoids and spheroids, hold great potential for studying morphogenesis, disease modeling, and drug discovery. However, sub-cellular resolution 3D imaging of these biological samples ...

Royal Society of Chemistry (RSC)2025

A Flat Tendon-Driven Continuum Microrobot for Brain Interventions

Mahmut Selman Sakar, Lorenzo Francesco John Noseda, Lucio Feo Pancaldi-Giubbini

Navigating biomedical instruments inside the brain remains challenging and high-risk. The delicate nature of the tissues involved requires the development of cutting-edge robotic technologies to enhance precision and safety. In response to these demands, t ...

Institute of Electrical and Electronics Engineers Inc.2024

Precise tactile stimulation of worker ants by a robotic manipulator reveals that individual responses are density‐ and context‐dependent

Mahmut Selman Sakar, Laurent Keller, Alexandre Tuleu, Matthias Rüegg

2024

3D printed large amplitude torsional microactuators powered by ultrasound

Mahmut Selman Sakar, Mehdi Ali Gadiri, Junsun Hwang, Amit Yedidia Dolev

Here, we introduce a design, fabrication, and control methodology for large amplitude torsional microactuators powered by ultrasound. The microactuators are 3D printed from two polymers with drastically different elastic moduli as a monolithic compliant me ...

2024

Modeling the mechanosensitive collective migration of cells on the surface and the interior of morphing soft tissues

Mahmut Selman Sakar, Jaemin Kim

Cellular contractility, migration, and extracellular matrix (ECM) mechanics are critical for a wide range of biological processes including embryonic development, wound healing, tissue morphogenesis, and regeneration. Even though the distinct response of c ...

Springer Science and Business Media LLC2024

Targeted worker removal reveals a lack of flexibility in brood transport specialisation with no compensatory gain in efficiency

Mahmut Selman Sakar, Laurent Keller, Fazil Emre Uslu

Division of labour is widely thought to increase the task efficiency of eusocial insects. Workers can switch their task to compensate for sudden changes in demand, providing flexible task allocation. In combination with automated tracking technology, we de ...

Nature Research2024

A Robotic Surgery Platform for Automated Tissue Micromanipulation in Zebrafish Embryos

Andrew Charles Oates, Mahmut Selman Sakar, Ece Özelçi, Laurel Ann Rohde, Erfan Etesami

Microsurgical manipulations are key experimental techniques in life science research, particularly in embryology. These techniques are most often performed manually by highly skilled scientists, posing limitations on speed, precision, and reproducibility. ...

2024

Small-scale robotic devices for medical interventions in the brain

Mahmut Selman Sakar, Lorenzo Francesco John Noseda

This article summarizes the recent advancements in the design, fabrication, and control of microrobotic devices for the diagnosis and treatment of brain disorders. With a focus on diverse actuation methods, we discuss how advancements in materials science ...

2024

A graduate laboratory experiment to study the dynamics of an acoustically levitated particle

Mahmut Selman Sakar, Lorenzo Francesco John Noseda, Amit Yedidia Dolev, Bora Yalcin

The comprehension of physical wave phenomena is imperative for students in the fields of engineering and basic sciences. Laboratory experiments that involve generation of acoustic waves can be used to explain advanced nonlinear wave phenomena. Acoustic lev ...

2023