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Yueyun Zhang

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Related units (1)

Prof. Brisken Group

EPFL
SV
ISREC
UPBRI

Method for hormone or drug screening in a tissue sample

Cathrin Brisken, Christoph Merten, Yueyun Zhang

The present invention relates to a method for analyzing cellular responsiveness to hormones or drags in a tissue sample based on an alginate-based 3D ex vivo culture system for normal and malignant tissue microstructures and uses thereof. ...

2023

ER+ breast cancer in 3D scaffold ex vivo for transcriptomics-based functional drug screening and personalized medicine

Breast cancer (BC) is the most diagnosed cancer and a leading cause of cancer-related mortality for women worldwide (Bray Bsc et al. 2024). It is a heterogeneous disease with 19 special histopathological subtypes and 5 molecular subtypes (Tavassoli and Dev ...

EPFL2024

Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence

Cathrin Brisken, Giovanna Ambrosini, Georgios Sflomos, Yueyun Zhang, Hazel Margaret Quinn, Fabio De Martino, Patrik Aouad, Céline Marie Victoria Stibolt, Kelly Spry Maggs

More than 70% of human breast cancers (BCs) are estrogen receptor α-positive (ER+). A clinical challenge of ER+ BC is that they can recur decades after initial treatments. Mechanisms governing latent disease remain elusive due to lack of adequate in vivo m ...

Nature Research2022