Publications by Gian Luca Barbruni

A More Reliable Equivalent Circuit of Electrochemical Sensors for Robust Design of CMOS Front-ends

Sandro Carrara, Gian Luca Barbruni, Ali Meimandi

Electrochemical sensors integrated with CMOS circuits play a pivotal role in quantifying various chemicals across a huge spectrum of applications, prominently in distributed diagnostics and remote monitoring. When designing integrated devices, meticulous c ...

2025

New Sensory Method for Neural Activity by Frequency Upconversion With Nonlinear Element

Sandro Carrara, Gian Luca Barbruni, Ali Meimandi

Traditional analog front-ends for biomedical signal acquisitions operate at very low frequencies (Hz-range) and are severely affected by flicker and environmental noise, which degrade the quality of low-frequency signals, thereby reducing the signal-to-noi ...

2024

A modular multiple frequency inductive link to wirelessly power multiple miniaturized implants

Sandro Carrara, Diego Ghezzi, Gian Luca Barbruni

A modular multiple frequency coils inductive link system to wirelessly provide power for at least a medical implant at an output of a receiving coil, whereby the receiving coil is configured to be implanted in an organism. The modular multiple frequency co ...

2024

Enhancing Prostate Cancer Diagnosis with In-Memory Sensing and Edge Computing of Percent-free PSA Index

Sandro Carrara, Gian Luca Barbruni, Ata Jedari Golparvar

In this paper, we are presenting a new architecture to directly compute the ‘Percent-free PSA’ diagnostics index to enhance the differentiation of prostate cancer from benign prostatic disease. The proposed circuit uses silicon nanowires-based memristive b ...

Institute of Electrical and Electronics Engineers Inc.2024

A Frequency-Switching Inductive Power Transfer System for Wireless, Miniaturised and Large-Scale Neural Interfaces

Sandro Carrara, Diego Ghezzi, Gian Luca Barbruni

Three-coil inductive power transfer is the state-of-the-art solution to power multiple miniaturised neural implants. However, the maximum delivered power is limited by the efficiency of the powering link and safety constrains. Here we propose a frequency-s ...

Ieee-Inst Electrical Electronics Engineers Inc2024

In-Memory Sensing and Computing for Cancer Diagnostics: A Perspective Paper

Sandro Carrara, Gian Luca Barbruni, Junrui Chen, Ata Jedari Golparvar

During the past two decades, a number of two-terminal switching devices have been demonstrated in the literature. They typically exhibit hysteric behavior in the current-to-voltage characteristics. These devices have often been also referred to as memristi ...

Ieee-Inst Electrical Electronics Engineers Inc2024

A 69 µm2 Sub-nW/kHz Capacitor-less Ring Oscillator for Ultra-Miniaturized Implants

Sandro Carrara, Gian Luca Barbruni, Ali Meimandi

This paper presents an ultra-miniaturized, ultra-low-power, capacitor-less CMOS ring oscillator based on dynamic leakage suppression technique. Measurement results demonstrated an oscillation frequency of 21.89 kHz and a power consumption of 7.9 nW for a s ...

Institute of Electrical and Electronics Engineers Inc.2024

A Wearable Real-Time System for Simultaneous Wireless Power and Data Transmission to Cortical Visual Prosthesis

Sandro Carrara, Gian Luca Barbruni

Wireless, miniaturised and distributed neural interfaces are emerging neurotechnologies. Although extensive research efforts contribute to their technological advancement, the need for real-time systems enabling simultaneous wireless information and power ...

Ieee-Inst Electrical Electronics Engineers Inc2024

Development of an Integrated CMUTs-Based Resonant Biosensor for Label-Free Detection of DNA with Improved Selectivity by Ethylene- Glycol Alkanethiols

Sandro Carrara, Gian Luca Barbruni, Yihe Zhao

Gravimetric resonant-inspired biosensors have attracted increasing attention in industrial and point-of- care applications, enabling label-free detection of biomarkers such as DNA and antibodies. Capacitive micromachined ultrasonic transducers (CMUTs) are ...

ELSEVIER2024

Bodily implant microelectrode and bodily implant microelectrode fabrication method

Sandro Carrara, Diego Ghezzi, Gian Luca Barbruni

The present invention concerns a bodily implantable or probe device and microelectrode fabrication method comprising providing at least one silicon substrate including an electronic device or unit; providing, on a first side of the silicon substrate, at le ...

2024