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Keshav Jha

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Centriole elimination during Caenorhabditis elegans oogenesis initiates with loss of the central tube protein SAS-1

Pierre Gönczy, Coralie Busso, Alexander Woglar, Mary-Claude Croisier-Coeytaux, Tamara Mikeladze-Dvali, Keshav Jha, Marie Juliette Ségolène Pierron

In most metazoans, centrioles are lost during oogenesis, ensuring that the zygote is endowed with the correct number of two centrioles, which are paternally contributed. How centriole architecture is dismantled during oogenesis is not understood. Here, we ...

Wiley2023

Related units (1)

Prof. Gönczy Group

EPFL
SV
ISREC
UPGON

Molecular architecture of the C. elegans centriole

Pierre Gönczy, Coralie Busso, Alexander Woglar, Keshav Jha, Marie Juliette Ségolène Pierron, Fabian Zacharias Schneider

Uncovering organizing principles of organelle assembly is a fundamental pursuit in the life sciences. Caenorhabditis elegans was key in identifying evolutionary conserved components governing assembly of the centriole organelle. However, localizing these c ...

2022

Dissecting the mechanisms of centriole stability in Caenorhabditis elegans: Focus on SAS-1

Centrioles are evolutionarily conserved microtubule-based organelles essential for cell division, ciliogenesis, and cell polarity. While centrioles are critical for many cellular processes, their selective elimination is crucial during specific development ...

EPFL2025