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Jia Liu

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https://people.epfl.ch/yasmine.liu

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Related units (1)

Laboratory of Integrative Systems Physiology

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Related publications (16)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

A lysosomal surveillance response to stress extends healthspan

Johan Auwerx, Xiaoxu Li, Tanes Imamura de Lima, Jia Liu, Qi Wang, Wen Gao, Yang Li, Amélia Lalou

Lysosomes are cytoplasmic organelles central for the degradation of macromolecules to maintain cellular homoeostasis and health. However, how lysosomal activity can be boosted to counteract ageing and ageing-related diseases remains elusive. Here we reveal ...

Springer Science and Business Media LLC2025

Mitochondrial genetics, signalling and stress responses

Johan Auwerx, Jia Liu

Mitochondria are multifaceted organelles with crucial roles in energy generation, cellular signalling and a range of synthesis pathways. The study of mitochondrial biology is complicated by its own small genome, which is matrilineally inherited and not sub ...

NATURE PORTFOLIO2025

ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH

Johan Auwerx, Xiaoxu Li, Jia Liu, Qi Wang, Sandra Rodriguez Lopez, Keno Strotjohann

Background & Aims: Recent findings reveal the importance of tryptophan-initiated de novo nicotinamide adenine dinucleotide (NAD+) synthesis in the liver, a process previously considered secondary to biosynthesis from nicotinamide. The enzyme α-amino-β-carb ...

2025