Label-free detection of DNA with interdigitated micro-electrodes in a fluidic cell
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Neuroprostheses were developed for a variety of applications using unique microfabrication methods. A technology platform that enables novel microelectrode array designs and microfluidic channels is described. Experiments demonstrating the in vivo utility ...
lectrical deep brain stimulation (DBS) is an efficient method to treat movement disorders. Many models of DBS, based mostly on finite elements, have recently been proposed to better understand the interaction between the electrical stimulation and the brai ...
Using B. Zotter’s formalism, we present here a novel, efficient and exact matrix method for the field matching determination of the electromagnetic field components created by an offset point charge travelling at any speed in an infinitely long circular mu ...
In this review we present a unified approach for single cell dielectric spectroscopy. Impedance spectroscopy and dielectrophoretic cell sorting, current microtechnologies applied in electrical analysis of single cells are discussed based on their closely r ...
We report on the microfabrication and testing of a chip- scale plasma light source. The device consists of a stack of three anodically bonded Pyrex wafers, which hermetically enclose a gas-filled cavity containing interdigitated Aluminum electrodes. When t ...
This thesis presents the fabrication and design of an impedance imaging sensor, and its application to monitoring in-vitro skin culture. Three-dimensional tissue cultures are becoming increasingly important in biological and medical research. There is, how ...
The commercial application of biosensors has had a significant impact in a number of areas, particularly in the field of medical diagnostics. But in spite of the great number of publications, only a few systems are commercially available in food analysis. ...
This thesis reports on the integration of continuous-flow cell separation method for lab-on-a-chip applications. Cell separation methods are widely used in biology to prepare samples prior to analysis. There is a need for a highly sensitive separation meth ...
Two types of DNA biosensors are presented. Both sensing principles are demonstrated using synthetic oligomer single-stranded DNA (ssDNA) with concentrations in the micromolar range. A first sensor type is based on the detection of fluorescently labeled ssD ...
A point-contact model is presented, and an areacontact model has been analytically derived in order to model the electrical characteristic of the cell-electrode interface of high-density neuron cultures. The area-contact model is presented as a model more ...