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Extended focus Fourier domain optical coherence microscopy assists developmental biology

Related publications (68)

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Cumulant microscopy

Theo Lasser, Claudio Dellagiacoma, Stefan Geissbuehler

The invention describes a method and a microscopy system for imaging and analysing stochastically and independently blinking point-like emitters. A multiple-order cumulants analysis in conjunction with an established blinking model enables the extraction o ...

2012

Sensitivity of X-ray grating interferometry

Peter Modregger, Simon Rutishauser, Christian David, Marco Stampanoni

It is known that the sensitivity of X-ray phase-contrast grating interferometry with regard to electron density variations present in the sample is related to the minimum detectable refraction angle. In this article a numerical framework is developed that ...

Optical Society of America2011

Dual wavelength full field imaging in low coherence digital holographic microscopy

Christian Depeursinge, Christophe Moser, Frédéric Montfort, Zahra Monemhaghdoust

A diffractive optical element (DOE) is presented to simultaneously manipulate the coherence plane tilt of a beam containing a plurality of discrete wavelengths. The DOE is inserted into the reference arm of an off-axis dual wavelength low coherence digital ...

Optical Society of America2011

Extended Focus Optical Coherence Microscopy

Martin Villiger

Optical coherence tomography (OCT) is an interferometric imaging technique that can provide depth resolved cross-sectional views of biological tissue. OCT employs light with low temporal and yet high spatial coherence. The sample is illuminated point by po ...

EPFL2010

Dark-field optical coherence microscopy

Theo Lasser, Christophe Pache, Martin Villiger

Dark-field illumination is known to enhance scattering contrast in optical microscopy. We combined this concept with Fourier domain optical coherence microscopy (OCM). The detection and illumination paths are decoupled, and only the scattered light origina ...

Optical Society of America2010

Optofluidic pressure sensor based on interferometric imaging

Demetri Psaltis, Wuzhou Song

We present a chip-scale optofluidic interferometric sensor for measuring liquid pressure based on an imaging method. The chip was constructed with a polymer by multilayer soft lithography. It consists of a flexible air gap optical cavity, which, upon illum ...

2010

Phase extraction in dynamic speckle interferometry: proposal of a road map

Sébastien Equis

Of all the two-beam interference patterns, the ones obtained in speckle interferometry (SI) are the most difficult to be phase-demodulated. Many solutions exist in classical smooth-wave interferometry and alike techniques, both in static and dynamic regime ...

E D P Sciences, 17 Ave Du Hoggar Parc D Activites Countboeuf Bp 112, F-91944 Cedex A, France2010

Multiple-wavelength digital holographic microscopy

Jonas Kühn

In this thesis work, we extend digital holographic microscopy (DHM) capabilities and applications range by using from two to twenty different wavelength laser sources, either simultaneously or sequentially. As an overview, we present methods to increase th ...

EPFL2009

Engineering of Extended Focii for Optical Coherence Microscopy

Theo Lasser, Christophe Pache, Rainer Leitgeb, Martin Villiger, Simon Rutishauser

Based on a Debye integral approach, we engineered an extended focal field distribution for Fourier domain optical coherence microscopy. This simulation optimizes beam con- figurations for high lateral resolution combined with extended depth of field. ...

2009

Towards in vivo small animal imaging

Theo Lasser, Michael Friedrich, Rainer Leitgeb, Anne Grapin-Botton, Martin Villiger, Joan Goulley

Fourier domain Optical coherence microscopy (FDOCM) offers excellent sensitivity and high axial resolution to image the structure of biological tissue. The depth information is extracted in parallel and allows very high volume acquisition rates. An illumin ...

2008