Publication
High-density collagen gel tubes as a matrix for primary human bladder smooth muscle cells
Related publications (36)
Mechanical Characterisation of Porcine Urethra: Non Linear Constitutive Models and Experimental Approach
Yves Perriard, Yoan René Cyrille Civet, Thomas Guillaume Martinez, Stefania Maria Aliki Konstantinidi, Amine Benouhiba, Quentin Philippe Mario De Menech
Low urinary tract dysfunctions and symptoms (LUTS) and Urinary incontinence (UI) in particular is a medical condition that affects millions of people worldwide. One of the most promising long term treatments for this condition is the use of an artificial u ...
IEEE2023Decoding bladder state from pudendal intraneural signals in pigs
Silvestro Micera, Stéphanie Lacour, Leonardo Pollina, Ivo Strauss, Valentina Marie Paggi
Neuroprosthetic devices used for the treatment of lower urinary tract dysfunction, such as incontinence or urinary retention, apply a pre-set continuous, open-loop stimulation paradigm, which can cause voiding dysfunctions due to neural adaptation. In the ...
2023Molecular Regulation of Muscle Stem Cell Fate during Skeletal Muscle Regeneration and Aging
Muscle stem cells (MuSCs) are the primary source of myogenic progenitors during muscle repair and are essential for the long-term regenerative capacity of skeletal muscle. Following myofiber injury, MuSCs transition from a quiescent to an activated state, ...
EPFL2022Towards an in vitro cardiac model: 3D environment, co-culture, alignment, and mechanical stimulation impact on cell behavior
Our aim is to develop a 3D model unit of cardiac muscle: an in-vitro analog of the trabeculae carneae found in vivo. As a base hydrogel matrix for cardiomyocyte culture in 3D, we develop a blend of decellularized extracellular matrix (dECM) and fibrin. Thi ...
EPFL2021Microtissue models for studying the dynamics of host-pathogen interactions in the urinary bladder
Urinary tract infections (UTIs) are amongst the most common bacterial infections and are the second-most frequent reason for antibiotic prescriptions. Moreover, in about 25% of all treated cases, recurrence of infection occurs. Uropathogenic Escherichia co ...
EPFL2021CO-REGULATION OF ENDOTHELIAL AND MYOGENIC CELL FATES THROUGH INTERCELLULAR CROSSTALK IN SKELETAL MUSCLE
Skeletal muscle is one of the most dynamic organs in the human body, which has a vigorous potential to regenerate and adapt to environmental changes. Depending on environments, skeletal muscle enables essential life activities to survive by controlling mov ...
EPFL2021Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection
John McKinney, Neeraj Dhar, Vivek Vijay Thacker, François Signorino-Gelo, Kunal Sharma, Thomas Marie Simonet
Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells to form intracellular bacterial communities (IBCs) during early stages of urinary tract infections. However, the dynamic responses of IBCs to host stresses and anti ...
2021Thoughts on cartilage tissue engineering: A 21st century perspective
Dominique Pioletti, Peyman Karami, Theofanis Stampoultzis
In mature individuals, hyaline cartilage demonstrates a poor intrinsic capacity for repair, thus even minor defects could result in progressive degeneration, impeding quality of life. Although numerous attempts have been made over the past years for the ad ...
2021Neural circuits of idiopathic Normal Pressure Hydrocephalus: A perspective review of brain connectivity and symptoms meta-analysis
Dimitri Nestor Alice Van De Ville, Alessandra Griffa
Idiopathic normal pressure hydrocephalus (iNPH) is a prevalent reversible neurological disorder characterized by impaired locomotion, cognition and urinary control with ventriculomegaly. Symptoms can be relieved with cerebrospinal fluid drainage, which mak ...
PERGAMON-ELSEVIER SCIENCE LTD2020Development of a biologically inspired in-vitro platform for long-term assessment of commercial and innovative ureteral stents
Yves Perriard, Yoan René Cyrille Civet, Francesco Clavica
Ureteral stents are small flexible tubes which are clinically used to restore the urine drainage in presence of obstructions of the ureteral lumen such as tumours, kidney/ureteral stones. The lifetime risk of developing urinary stones is about 20% in men a ...
2019