Autofluorescence detection of tumors in the human lung - spectroscopical measurements in situ, in an in vivo model and in vitro
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The detn. of residual dipolar couplings (RDCs) by quant. J spectroscopy methods such as heteronuclear single quantum correlation with phase encoded coupling (HSQC-PEC) is prone to systematic errors that may be caused by differential attenuation during the ...
Image and flow cytometry was used to study the nuclear DNA content (ploidy) during the squamous cell carcinogenesis in the esophagus. The present retrospective study comprised 26 surgical specimens of squamous cell carcinomas (SCC) in patients who underwen ...
The early detection and localization of bronchial cancer remains a challenging task. Autofluorescence bronchoscopy is emerging as a useful diagnostic tool with improved sensitivity and specificity. Evidence exists that the native fluorescence or autofluore ...
Autofluorescence is emerging as a useful tool for the detection of early cancers in the bronchi. It has already produced interesting results, which have been implemented in commercial imaging devices. Their design relies on the spectroscopy of the tissues ...
2001
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Early detection and localisation of bronchial cancer remains a challenging task. One approach is to exploit the changes in the autofluorescence characteristics of the bronchial tissue as a diagnostic tool with improved sensitivity. Evidence exists that thi ...
2001
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We calc. the effects of relatively strong elec. fields, corresponding to typical values for the fields inside glasses and proteins, on the spectroscopic properties of a simple two-level mol. Disorder in the elec. field strength is employed as a phys. sourc ...
2001
The environment is important for the exact course of a chemical reaction. As an example of the strong influence of the environment on the reaction, this work studies the isomerization reaction of the chromophore retinal in the binding pocket of the protein ...
EPFL2004
The aim of this thesis is to optimize and obtain fundamental information on i) the photodetection (PD) of early stage cancers in the tracheo-bronchial tree by spectroscopic imaging of the tissue autofluorescence, ii) photodynamic therapy (PDT) applied in d ...
The detn. of residual dipolar couplings (RDCs) by quant. J spectroscopy methods such as heteronuclear single quantum correlation with phase encoded coupling (HSQC-PEC) is prone to systematic errors that may be caused by differential attenuation during the ...