Quantitative diffuse reflectance and transmittance spectroscopy of loosely packed powders
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In the pharmaceutical industry, batch crystallization processes at production scale are not always well understood. Several factors have a significant impact on the process of crystallization, such as the physicochemical properties (solubility curve and su ...
The three-dimensional (3D) structures of proteins and peptides in vivo largely determine their biological functions. In vitro these native structures and their heterogeneity reflect a subtle balance between noncovalent intramolecular interactions and those ...
The recent phenomenal growth of the field of biotechnology has contributed to a mounting pressure to improve process efficiency and productivity and to increase the quality and safety of end-products. This demand gave rise to the discipline of on-line biop ...
The combination of EPR and Mossbauer spectroscopy along with IR, Diffuse Reflectance UV-visible, and XRD techniques proved to be a powerful tool for identifying and characterizing the mol. and electronic structure of various Fe complexes formed inside the ...
Because of the importance of helices in the secondary structure of proteins, we have undertaken a study of their spectroscopy, fragmentation patterns and conformations in the gas phase. In this work, we describe the effects of substitution at the N-terminu ...
This thesis aimed at developing new, simple methods of calibration for on-line monitoring of bioprocesses by Fourier-transform mid-infrared spectroscopy (FTIR). The conventional calibration approach implies the preparation and measurement of a large number ...
We present a MEMS infrared spectrometer for selective and quantitative chemical gas analysis. infrared absorption spectroscopy can distinguish gases easily and also detect nonreactive molecules like CO2, in contrast to e.g. metal oxide gas sensors The foll ...
The environment is important for the exact course of a chemical reaction. As an example of the strong influence of the environment on the reaction, this work studies the isomerization reaction of the chromophore retinal in the binding pocket of the protein ...
Spectromicroscopy with the imaging technique of X-ray photoelectron emission microscopy (X-PEEM) is a microchemical analytical tool installed in many synchrotron radiation laboratories, and which is finding application in diverse fields of research. The me ...
In the moderate magneticfield of TCV (1.5T), the recently installed X3 system (3 gyrotrons @118 GHz, 0.45 MW/each, 2s) broadens the operational space with the possibility of heating plasmas at high density, well above the cutoff density of the X2 system (X ...