A molecular probe for the optical detection of biogenic amines
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This Ph.D. work deals with the development of lanthanide-based bioprobes for biomedical analyses and imaging. For this purpose, two different approaches have been followed, one focusing on visible-emitting complexes, while the second addresses the sensitiz ...
The environment is important for the exact course of a chemical reaction. As an example of the strong influence of the environment on the reaction, this work studies the isomerization reaction of the chromophore retinal in the binding pocket of the protein ...
An organometallic 4d transition metal complex [CpRhCl2]2, together with commercially available dyes, was used to construct indicator displacement assays (IDAs) for the detection of peptides, amino acids, and nucleotides. The combination of the CpRh compl ...
We review fundamental and applied acid-base equilibrium chemistry useful to microfluidic electrokinetics. We present elements of acid-base equilibrium reactions and derive rules for pH calculation for simple buffers. We also present a general formulation t ...
To study the physicochemical properties of the DTTA chelating moiety (H4DTTA = diethylenetriaminetetraacetic acid = N,N′-[iminobis(ethane-2,1-diyl)]bis[N-(carboxymethyl)glycine]), used in several compounds proposed as magnetic resonance imaging (MRI) contr ...
The optical properties of small noble metal clusters have been studied by absorption and fluorescence for sizes between 1 and 10 atoms. The experimental technique consists in depositing size-selected clusters in a neon matrix and analyzing with a spectrome ...
Indicator displacement assays based on the organometallic complex [Cp*RhCl2]2 and the dye gallocyanine have been used to sense aminosugars and aminoglycosides in buffered aqueous solution by UV-Vis spectroscopy. The data of three assays at pH 7.0, 8.0 and ...
Two novel tetra- and hexahydroxy functionalized perylene chromophores have been used as initiators for the Sn(oct)2 catalyzed ring-opening polymerization of different lactones. The arms of the resulting star polymers were comprised of either crystallizable ...
The development of a new assay for lipoproteins by capillary electrophoresis in fused-silica capillaries and in glass microdevices is described in this paper. The separation of low-density (LDL) and high-density (HDL) lipoproteins by capillary zone electro ...
The authors present photon echo peak shift and femtosecond fluorescence up-conversion studies of nonpolar solvation dynamics of a simple nonpolar dye p-terphenyl in EtOH and cyclohexane, using excitation in the UV range at 290 nm. The UV fluorescence up-co ...