A Handheld Intra-Operative beta(+) Sensing System

We present a new, handheld system for in vivo detection of radiotracers. The detection is based on scintillators coupled to Silicon Photomultipliers (SiPMs) and aimed at direct positron detection. The battery-powered system is wire-lessly connected to a PC. A graphical user interface allows controlling the probe functions and monitoring count rates, battery voltage and temperature. The probe is fully compatible with standard sterilisation procedures and has been successfully used in pre-clinical trials with human cancer patients. The use of the probe requires that the patient be administered a dose of the radiopharmaceutical F-18-fluorodeoxyglucose (FDG), a beta(+) emitting glucose analogue used for detecting tumours in oncology, which can still be detected during the operation. (C) 2011 Published by Elsevier Ltd.

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Edoardo Charbon, Claudio Bruschini, Marco Matter, Christian Mester
2011
Conference paper

Abstract

Official source

https://infoscience.epfl.ch/record/178449?ln=en

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Related concepts (2)

Graphical user interface

The graphical user interface, or GUI (ˌdʒi:juːˈaɪ or ˈɡu:i ), is a form of user interface that allows users to interact with electronic devices through graphical icons and audio indicators such as primary notation, instead of text-based UIs, typed command labels or text navigation. GUIs were introduced in reaction to the perceived steep learning curve of command-line interfaces (CLIs), which require commands to be typed on a computer keyboard. The actions in a GUI are usually performed through direct manipulation of the graphical elements.

Scintillator

A scintillator ('sɪntɪleɪtər ) is a material that exhibits scintillation, the property of luminescence, when excited by ionizing radiation. Luminescent materials, when struck by an incoming particle, absorb its energy and scintillate (i.e. re-emit the absorbed energy in the form of light). Sometimes, the excited state is metastable, so the relaxation back down from the excited state to lower states is delayed (necessitating anywhere from a few nanoseconds to hours depending on the material).