Calcium metabolismCalcium metabolism is the movement and regulation of calcium ions (Ca2+) in (via the gut) and out (via the gut and kidneys) of the body, and between body compartments: the blood plasma, the extracellular and intracellular fluids, and bone. Bone acts as a calcium storage center for deposits and withdrawals as needed by the blood via continual bone remodeling. An important aspect of calcium metabolism is plasma calcium homeostasis, the regulation of calcium ions in the blood plasma within narrow limits.
Detection theoryDetection theory or signal detection theory is a means to measure the ability to differentiate between information-bearing patterns (called stimulus in living organisms, signal in machines) and random patterns that distract from the information (called noise, consisting of background stimuli and random activity of the detection machine and of the nervous system of the operator). In the field of electronics, signal recovery is the separation of such patterns from a disguising background.
CaesiumCaesium (IUPAC spelling; cesium in American English) is a chemical element with the symbol Cs and atomic number 55. It is a soft, silvery-golden alkali metal with a melting point of , which makes it one of only five elemental metals that are liquid at or near room temperature. Caesium has physical and chemical properties similar to those of rubidium and potassium. It is pyrophoric and reacts with water even at . It is the least electronegative element, with a value of 0.79 on the Pauling scale.
Sensitivity and specificitySensitivity and specificity mathematically describe the accuracy of a test that reports the presence or absence of a condition. If individuals who have the condition are considered "positive" and those who do not are considered "negative", then sensitivity is a measure of how well a test can identify true positives and specificity is a measure of how well a test can identify true negatives: Sensitivity (true positive rate) is the probability of a positive test result, conditioned on the individual truly being positive.
Arctic oscillationThe Arctic oscillation (AO) or Northern Annular Mode/Northern Hemisphere Annular Mode (NAM) is a weather phenomenon at the Arctic pole north of 20 degrees latitude. It is an important mode of climate variability for the Northern Hemisphere. The southern hemisphere analogue is called the Antarctic oscillation or Southern Annular Mode (SAM). The index varies over time with no particular periodicity, and is characterized by non-seasonal sea-level pressure anomalies of one sign in the Arctic, balanced by anomalies of opposite sign centered at about 37–45° N.
Signal transductionSignal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events. Most commonly, protein phosphorylation is catalyzed by protein kinases, ultimately resulting in a cellular response. Proteins responsible for detecting stimuli are generally termed receptors, although in some cases the term sensor is used. The changes elicited by ligand binding (or signal sensing) in a receptor give rise to a biochemical cascade, which is a chain of biochemical events known as a signaling pathway.
CadmiumCadmium is a chemical element with the symbol Cd and atomic number 48. This soft, silvery-white metal is chemically similar to the two other stable metals in group 12, zinc and mercury. Like zinc, it demonstrates oxidation state +2 in most of its compounds, and like mercury, it has a lower melting point than the transition metals in groups 3 through 11. Cadmium and its congeners in group 12 are often not considered transition metals, in that they do not have partly filled d or f electron shells in the elemental or common oxidation states.
Ryanodine receptorRyanodine receptors (RyR for short) form a class of intracellular calcium channels in various forms of excitable animal tissue like muscles and neurons. There are three major isoforms of the ryanodine receptor, which are found in different tissues and participate in different signaling pathways involving calcium release from intracellular organelles. The RYR2 ryanodine receptor isoform is the major cellular mediator of calcium-induced calcium release (CICR) in animal cells.
North Atlantic oscillationThe North Atlantic Oscillation (NAO) is a weather phenomenon over the North Atlantic Ocean of fluctuations in the difference of atmospheric pressure at sea level (SLP) between the Icelandic Low and the Azores High. Through fluctuations in the strength of the Icelandic Low and the Azores High, it controls the strength and direction of westerly winds and location of storm tracks across the North Atlantic. The NAO was discovered through several studies in the late 19th and early 20th centuries.
