Lebesgue measureIn measure theory, a branch of mathematics, the Lebesgue measure, named after French mathematician Henri Lebesgue, is the standard way of assigning a measure to subsets of n-dimensional Euclidean space. For n = 1, 2, or 3, it coincides with the standard measure of length, area, or volume. In general, it is also called n-dimensional volume, n''-volume, or simply volume. It is used throughout real analysis, in particular to define Lebesgue integration.
ClustalClustal is a series of widely used computer programs used in bioinformatics for multiple sequence alignment. There have been many versions of Clustal over the development of the algorithm that are listed below. The analysis of each tool and its algorithm is also detailed in their respective categories. Available operating systems listed in the sidebar are a combination of the software availability and may not be supported for every current version of the Clustal tools.
Substitution matrixIn bioinformatics and evolutionary biology, a substitution matrix describes the frequency at which a character in a nucleotide sequence or a protein sequence changes to other character states over evolutionary time. The information is often in the form of log odds of finding two specific character states aligned and depends on the assumed number of evolutionary changes or sequence dissimilarity between compared sequences. It is an application of a stochastic matrix.
PfamPfam is a database of protein families that includes their annotations and multiple sequence alignments generated using hidden Markov models. The most recent version, Pfam 35.0, was released in November 2021 and contains 19,632 families. The general purpose of the Pfam database is to provide a complete and accurate classification of protein families and domains. Originally, the rationale behind creating the database was to have a semi-automated method of curating information on known protein families to improve the efficiency of annotating genomes.
Wire chamberA wire chamber or multi-wire proportional chamber is a type of proportional counter that detects charged particles and photons and can give positional information on their trajectory, by tracking the trails of gaseous ionization. The multi-wire chamber uses an array of wires at high voltage (anode), which run through a chamber with conductive walls held at ground potential (cathode). Alternatively, the wires may be at ground potential and the cathode held at a high negative voltage; the important thing is that a uniform electric field draws extra electrons or negative ions to the anode wires with little lateral motion.
