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Optical Coherence Correlation Spectroscopy (OCCS)

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We present a 3D time-lapse imaging method for monitoring mitochondrial dynamics in living HeLa cells based on photothermal optical coherence microscopy and using novel surface functionalization of gold nanoparticles. The biocompatible protein-based biopoly ...

Nature Publishing Group2017

Inorganic nanomaterials able to generate reactive oxygen species (ROS) are promising components for modern medical applications. Activated by near-infrared light, up-converting beta-NaYF4 doped with Er3+ - Yb3+ and Tm3+- Yb3+ pair ions nanoparticles (UCNPs ...

2017

Highly-sensitive distributed birefringence measurements based on a two-pulse interrogation of a dynamic Brillouin grating

Luc Thévenaz, Marcelo Alfonso Soto Hernandez, Andrey Denisov

A method for distributed birefringence measurements is proposed based on the interference pattern generated by the interrogation of a dynamic Brillouin grating (DBG) using two short consecutive optical pulses. Compared to existing DBG interrogation techniq ...

Ieee2017

An operando emission spectroscopy study of Pt/Al2O3 and Pt/CeO2/Al2O3

Davide Ferri, Oliver Kröcher

In situ time-resolved spectroscopic examination of catalysts based on well dispersed nanoparticles on metal oxides under transient conditions significantly facilitates the elucidation of reaction mechanisms. In this contribution, we demonstrate the level o ...

Royal Soc Chemistry2016

Selectivity Control in Palladium-Catalyzed Alcohol Oxidation through Selective Blocking of Active Sites

Davide Ferri, Oliver Kröcher, Di Wang

Stabilized metal nanoparticles (NPs) have received wide interest in a number of liquid-phase catalytic transformations, but the role of the capping/protective agent is still debated. Operando attenuated total reflection infrared (ATR-IR) spectroscopy enabl ...

American Chemical Society2016

Force sensitive hook for epiretinal membrane peeling in eye surgery

Charles Baur, Sebastian Krzysztof Fifanski, José Luis Rivera Gutiérrez

This project addresses the design, construction and evaluation of a peeling hook with force measurement capability for in-vivo intra-ocular vitreoretinal surgery. The force sensor consists of a miniature multi-degree-offreedom flexure where deformations in ...

2016

Multiscattering-Enhanced Absorption Spectroscopy

Olivier Martin, Christian Santschi, Volodymyr Koman

An original scheme for sensitive absorption measurements, particularly well-suited for low analyte concentrations, is presented. The technique is based on multiscattering-enhanced absorption spectroscopy (MEAS) and benefits from the advantages of conventio ...

Amer Chemical Soc2015

Questions such as biomolecular interactions, kinetics of enzymes, DNA conformational changes, cellular structures properties (among others) are addressed by characterizing the biological function of molecules. This function depends on their structure and t ...

EPFL2014

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Optical coherence correlation spectroscopy (OCCS) allows studying kinetic processes at the single particle level using the backscattered light of nanoparticles. We extend the possibilities of this technique by increasing its signal-to-noise ratio by a fact ...

Optical Society of America2014

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A classical technique to monitor dynamical processes at the single-molecule level is fluorescence correlation spectroscopy (FCS). However, FCS requires fluorescent labels that are typically limited by photobleaching and saturation. We present a new method, ...

2013