Constraint programmingConstraint programming (CP) is a paradigm for solving combinatorial problems that draws on a wide range of techniques from artificial intelligence, computer science, and operations research. In constraint programming, users declaratively state the constraints on the feasible solutions for a set of decision variables. Constraints differ from the common primitives of imperative programming languages in that they do not specify a step or sequence of steps to execute, but rather the properties of a solution to be found.
Bisulfite sequencingBisulfite sequencing (also known as bisulphite sequencing) is the use of bisulfite treatment of DNA before routine sequencing to determine the pattern of methylation. DNA methylation was the first discovered epigenetic mark, and remains the most studied. In animals it predominantly involves the addition of a methyl group to the carbon-5 position of cytosine residues of the dinucleotide CpG, and is implicated in repression of transcriptional activity.
MaintainabilityMaintainability is the ease of maintaining or providing maintenance for a functioning product or service. Depending on the field, it can have slightly different meanings. In engineering, maintainability is the ease with which a product can be maintained to: correct defects or their cause, Repair or replace faulty or worn-out components without having to replace still working parts, prevent unexpected working conditions, maximize a product's useful life, maximize efficiency, reliability, and safety, meet new requirements, make future maintenance easier, or cope with a changing environment.
