Nuclear magnetic resonance spectroscopy of proteinsNuclear magnetic resonance spectroscopy of proteins (usually abbreviated protein NMR) is a field of structural biology in which NMR spectroscopy is used to obtain information about the structure and dynamics of proteins, and also nucleic acids, and their complexes. The field was pioneered by Richard R. Ernst and Kurt Wüthrich at the ETH, and by Ad Bax, Marius Clore, Angela Gronenborn at the NIH, and Gerhard Wagner at Harvard University, among others.
Fat-tailed distributionA fat-tailed distribution is a probability distribution that exhibits a large skewness or kurtosis, relative to that of either a normal distribution or an exponential distribution. In common usage, the terms fat-tailed and heavy-tailed are sometimes synonymous; fat-tailed is sometimes also defined as a subset of heavy-tailed. Different research communities favor one or the other largely for historical reasons, and may have differences in the precise definition of either.
Random number generationRandom number generation is a process by which, often by means of a random number generator (RNG), a sequence of numbers or symbols that cannot be reasonably predicted better than by random chance is generated. This means that the particular outcome sequence will contain some patterns detectable in hindsight but unpredictable to foresight. True random number generators can be hardware random-number generators (HRNGs), wherein each generation is a function of the current value of a physical environment's attribute that is constantly changing in a manner that is practically impossible to model.
Scalar field theoryIn theoretical physics, scalar field theory can refer to a relativistically invariant classical or quantum theory of scalar fields. A scalar field is invariant under any Lorentz transformation. The only fundamental scalar quantum field that has been observed in nature is the Higgs field. However, scalar quantum fields feature in the effective field theory descriptions of many physical phenomena. An example is the pion, which is actually a pseudoscalar.
Effective field theoryIn physics, an effective field theory is a type of approximation, or effective theory, for an underlying physical theory, such as a quantum field theory or a statistical mechanics model. An effective field theory includes the appropriate degrees of freedom to describe physical phenomena occurring at a chosen length scale or energy scale, while ignoring substructure and degrees of freedom at shorter distances (or, equivalently, at higher energies).
History of quantum field theoryIn particle physics, the history of quantum field theory starts with its creation by Paul Dirac, when he attempted to quantize the electromagnetic field in the late 1920s. Heisenberg was awarded the 1932 Nobel Prize in Physics "for the creation of quantum mechanics". Major advances in the theory were made in the 1940s and 1950s, leading to the introduction of renormalized quantum electrodynamics (QED). QED was so successful and accurately predictive that efforts were made to apply the same basic concepts for the other forces of nature.
Wigner semicircle distributionThe Wigner semicircle distribution, named after the physicist Eugene Wigner, is the probability distribution on [−R, R] whose probability density function f is a scaled semicircle (i.e., a semi-ellipse) centered at (0, 0): for −R ≤ x ≤ R, and f(x) = 0 if |x| > R. The parameter R is commonly referred to as the "radius" parameter of the distribution. The Wigner distribution also coincides with a scaled beta distribution. That is, if Y is a beta-distributed random variable with parameters α = β = 3/2, then the random variable X = 2RY – R exhibits a Wigner semicircle distribution with radius R.
Coupling constantIn physics, a coupling constant or gauge coupling parameter (or, more simply, a coupling), is a number that determines the strength of the force exerted in an interaction. Originally, the coupling constant related the force acting between two static bodies to the "charges" of the bodies (i.e. the electric charge for electrostatic and the mass for Newtonian gravity) divided by the distance squared, , between the bodies; thus: in for Newtonian gravity and in for electrostatic.
Spin groupIn mathematics the spin group Spin(n) is a Lie group whose underlying manifold is the double cover of the special orthogonal group SO(n) = SO(n, R), such that there exists a short exact sequence of Lie groups (when n ≠ 2) The group multiplication law on the double cover is given by lifting the multiplication on . As a Lie group, Spin(n) therefore shares its dimension, n(n − 1)/2, and its Lie algebra with the special orthogonal group. For n > 2, Spin(n) is simply connected and so coincides with the universal cover of SO(n).
Length scaleIn physics, length scale is a particular length or distance determined with the precision of at most a few orders of magnitude. The concept of length scale is particularly important because physical phenomena of different length scales cannot affect each other and are said to decouple. The decoupling of different length scales makes it possible to have a self-consistent theory that only describes the relevant length scales for a given problem.
