Publications related to Functional and Structural Imaging with Optical Coherence Microscopy

AMPA receptor imaging by infrared scanning near-field optical microscopy

Giorgio Margaritondo, Kai Johnsson, Harald Hirling, Johanna Generosi, Michel Kropf

Infrared scanning near-field optical microscopy is used to detect AMPA-type glutamate receptor clusters in hippocampal neuron cells. AMPA's GluR2-subunits were marked with the fluorophore Alexa488 and high-resolution micrographs were taken at 6.25 µm wavel ...

2008

Extended focus Fourier domain optical coherence microscopy and fluorescence lifetime imaging

Theo Lasser, Rainer Leitgeb, Martin Villiger, Adrian Bachmann, Cédric Blatter

Fourier domain Optical coherence microscopy (FDOCM) offers excellent sensitivity and high axial resolution to image the structure of biological tissue. The depth information is extracted in parallel and allows very high volume acquisition rates. An illumin ...

SPIE2008

Acquisition et recalage informatique d'images confocales de tissus denses

Nicolas Fête

Analysis of the 3D structure of a biological sample is an important step to model cell and tissue dynamics. As a model system, we set up to determine the number of nuclei in a follicular papilla using confocal imaging and 3D computer reconstruction. The fo ...

EPFL2008

Video monitoring of neovessel occlusion induced by photodynamic therapy with verteporfin (Visudyne(r)), in the CAM model

Hubert van den Bergh, Georges Wagnières, Elodie Debefve

The aim of the present study was to monitor photodynamic angioocclusion with verteporfin in capillaries. Details of this process were recorded under a microscope in real-time using a high-sensitivity video camera. A procedure was developed based on intrave ...

Springer Netherlands2008

A Fast Thresholded Landweber Algorithm for General Wavelet Bases: Application to 3D Deconvolution Microscopy

Michaël Unser, Cédric René Jean Vonesch

Wavelet-domain

ℓ _{ 1 }

-regularization is a promising approach to deconvolution. The corresponding variational problem can be solved using a “thresholded Landweber” (TL) algorithm. While this iterative procedure is simple to implement, it is known to ...

IEEE2008

Rapid Immunoassay Using Steady-State Dispersion Effects in Nanochannels

Philippe Renaud, Nicolas Durand, Ana Valero

We present a novel method for on-chip competitive dispersion immunoassay (DISIA) which aims at measuring the specificity between fluorescently-labeled antibodies (Ab*) and label-free antigens (Ag). We have fabricated a nanofluidic device that allows fast d ...

2008

Detection efficiency in total internal reflection fluorescence microscopy

Theo Lasser, Marcel Leutenegger

We present a rapid and flexible framework for the accurate calculation of the detection efficiency of fluorescence emission in isotropic media as well as in the vicinity of dielectric or metallic interfaces. The framework accounts for the dipole characteri ...

2008

Triplet Imaging by Modulated Excitation

Dimitri Nestor Alice Van De Ville, Theo Lasser, Kai Johnsson, Boris Hinz, Thiemo Spielmann, Aurélie Formey de Saint Louvent

We present a functional imaging method based on triplet state kinetics. The triplet state of many known fluorophores show a triplet lifetime typically in the order of ~10e-6 – 10e-3 s, 3-6 orders of magnitude longer than the associated fluorescence singlet ...

2008

Joint co-clustering: Co-clustering of genomic and clinical bioimaging data

Giovanni De Micheli, Luca Benini

For better understanding the genetic mechanisms underlying clinical observations, and better defining a group of potential candidates for protein-family-inhibiting therapy, it is interesting to determine the correlations between genomic, clinical data and ...

Elsevier2008

Super-resolution from unregistered omnidirectional images

Pascal Frossard, Zafer Arican

This paper addresses the problem of super- resolution from low resolution spherical images that are not perfectly registered. Such a problem is typically en- countered in omnidirectional vision scenarios with re- duced resolution sensors in imperfect setti ...

2008

Functional and Structural Imaging with Optical Coherence Microscopy

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AMPA receptor imaging by infrared scanning near-field optical microscopy

Extended focus Fourier domain optical coherence microscopy and fluorescence lifetime imaging

Acquisition et recalage informatique d'images confocales de tissus denses

Video monitoring of neovessel occlusion induced by photodynamic therapy with verteporfin (Visudyne(r)), in the CAM model

A Fast Thresholded Landweber Algorithm for General Wavelet Bases: Application to 3D Deconvolution Microscopy

Rapid Immunoassay Using Steady-State Dispersion Effects in Nanochannels

Detection efficiency in total internal reflection fluorescence microscopy

Triplet Imaging by Modulated Excitation

Joint co-clustering: Co-clustering of genomic and clinical bioimaging data

Super-resolution from unregistered omnidirectional images

Acquisition et recalage informatique d'images confocales de tissus denses

Triplet Imaging by Modulated Excitation

Detection efficiency in total internal reflection fluorescence microscopy

Extended focus Fourier domain optical coherence microscopy and fluorescence lifetime imaging

AMPA receptor imaging by infrared scanning near-field optical microscopy

Video monitoring of neovessel occlusion induced by photodynamic therapy with verteporfin (Visudyne(r)), in the CAM model

Joint co-clustering: Co-clustering of genomic and clinical bioimaging data

Super-resolution from unregistered omnidirectional images

A Fast Thresholded Landweber Algorithm for General Wavelet Bases: Application to 3D Deconvolution Microscopy

Rapid Immunoassay Using Steady-State Dispersion Effects in Nanochannels