Wilcoxon signed-rank testThe Wilcoxon signed-rank test is a non-parametric statistical hypothesis test used either to test the location of a population based on a sample of data, or to compare the locations of two populations using two matched samples. The one-sample version serves a purpose similar to that of the one-sample Student's t-test. For two matched samples, it is a paired difference test like the paired Student's t-test (also known as the "t-test for matched pairs" or "t-test for dependent samples").
Conjugate priorIn Bayesian probability theory, if the posterior distribution is in the same probability distribution family as the prior probability distribution , the prior and posterior are then called conjugate distributions, and the prior is called a conjugate prior for the likelihood function . A conjugate prior is an algebraic convenience, giving a closed-form expression for the posterior; otherwise, numerical integration may be necessary. Further, conjugate priors may give intuition by more transparently showing how a likelihood function updates a prior distribution.
Human brainThe human brain is the central organ of the human nervous system, and with the spinal cord makes up the central nervous system. The brain consists of the cerebrum, the brainstem and the cerebellum. It controls most of the activities of the body, processing, integrating, and coordinating the information it receives from the sense organs, and making decisions as to the instructions sent to the rest of the body. The brain is contained in, and protected by, the skull bones of the head.
Substance dependenceSubstance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption of the drug. A drug addiction, a distinct concept from substance dependence, is defined as compulsive, out-of-control drug use, despite negative consequences.
Cocaine dependenceCocaine dependence is a neurological disorder that is characterized by withdrawal symptoms upon cessation from cocaine use. It also often coincides with cocaine addiction which is a biopsychosocial disorder characterized by persistent use of cocaine and/or crack despite substantial harm and adverse consequences. The Diagnostic and Statistical Manual of Mental Disorders (5th ed., abbreviated DSM-5), classifies problematic cocaine use as a "Stimulant use disorder". The International Classification of Diseases (11th rev.
Brain simulationBrain simulation is the concept of creating a functioning computer model of a brain or part of a brain. Brain simulation projects intend to contribute to a complete understanding of the brain, and eventually also assist the process of treating and diagnosing brain diseases. Various simulations from around the world have been fully or partially released as open source software, such as C. elegans, and the Blue Brain Project Showcase.
Space (mathematics)In mathematics, a space is a set (sometimes called a universe) with some added structure. While modern mathematics uses many types of spaces, such as Euclidean spaces, linear spaces, topological spaces, Hilbert spaces, or probability spaces, it does not define the notion of "space" itself. A space consists of selected mathematical objects that are treated as points, and selected relationships between these points. The nature of the points can vary widely: for example, the points can be elements of a set, functions on another space, or subspaces of another space.
P versus NP problemThe P versus NP problem is a major unsolved problem in theoretical computer science. In informal terms, it asks whether every problem whose solution can be quickly verified can also be quickly solved. The informal term quickly, used above, means the existence of an algorithm solving the task that runs in polynomial time, such that the time to complete the task varies as a polynomial function on the size of the input to the algorithm (as opposed to, say, exponential time).
Open setIn mathematics, an open set is a generalization of an open interval in the real line. In a metric space (a set along with a distance defined between any two points), an open set is a set that, along with every point P, contains all points that are sufficiently near to P (that is, all points whose distance to P is less than some value depending on P). More generally, an open set is a member of a given collection of subsets of a given set, a collection that has the property of containing every union of its members, every finite intersection of its members, the empty set, and the whole set itself.
Bounded setIn mathematical analysis and related areas of mathematics, a set is called bounded if it is, in a certain sense, of finite measure. Conversely, a set which is not bounded is called unbounded. The word "bounded" makes no sense in a general topological space without a corresponding metric. Boundary is a distinct concept: for example, a circle in isolation is a boundaryless bounded set, while the half plane is unbounded yet has a boundary. A bounded set is not necessarily a closed set and vice versa.
