Gene therapy and bioengineering for retinal diseases: what is the future?
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Purpose:Currently, there is no known cure for Retinitis pigmentosa (RP). Even if some treatments can slow down the progression of the disease, none of them can effectively stop retinal degeneration. We exploited the possibility of an early intervention in ...
PurposeTo evaluate the relationship between the peripapillary metabolic alterations [retinal vessel Oximetry (RO)] and the structural findings [retinal vessel diameter and retinal nerve fibre layer thickness (RNFL)] in patients with inherited retinal dystr ...
This report proposes an overview of the activities and services provided by the library to the School of engineering (STI) in 2014 as well as the STI collection accessible at the Library. It also presents the main projects that will be continued or initiat ...
The monocarboxylate transporter 1 (MCT1) is highly expressed in the outer retina, suggesting that it plays a critical role in photoreceptors. We examined MCT1+/- heterozygotes, which express half of the normal complement of MCT1. The MCT1(+/-) retina devel ...
This report proposes an overview of the activities and services provided by the Library to the School of engineering (STI) in 2016, as well as the STI collection accessible at the Library. It also presents the main projects that will be continued or initia ...
Replacement strategies arise as promising approaches in case of inherited retinal dystrophies leading to blindness. A fully organic retinal prosthesis made of conjugated polymers layered onto a silk fibroin substrate is engineered. First, the biophysical a ...
This report proposes an overview of the activities and services provided by the Library to the School of engineering (STI) in 2015, as well as the STI collection accessible at the Library. It also presents the main projects that will be continued or initia ...
Hereditary retinal degenerations encompass a group of genetic diseases characterized by extreme clinical variability. Following next-generation sequencing and autozygome-based screening of patients presenting with a peculiar, recessive form of cone-dominat ...
Most architectural modelling software provides the user with geometric freedom in absence of performance, while most engineering software mandates pre-determined forms before it can perform any numerical analysis. This trial-and-error process is not only t ...