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Extracting Atrial Activations from Intracardiac Signals during Atrial Fibrillation using Adaptive Mathematical Morphology

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Arrhythmia

Arrhythmias, also known as cardiac arrhythmias, heart arrhythmias, or dysrhythmias, are irregularities in the heartbeat, including when it is too fast or too slow. A resting heart rate that is too fast – above 100 beats per minute in adults – is called tachycardia, and a resting heart rate that is too slow – below 60 beats per minute – is called bradycardia. Some types of arrhythmias have no symptoms. Symptoms, when present, may include palpitations or feeling a pause between heartbeats.

Sinoatrial node

The sinoatrial node (also known as the sinuatrial node, SA node or sinus node) is an oval shaped region of special cardiac muscle in the upper back wall of the right atrium made up of cells known as pacemaker cells. The sinus node is approximately 15 mm long, 3 mm wide, and 1 mm thick, located directly below and to the side of the superior vena cava. These cells can produce an electrical impulse known as a cardiac action potential that travels through the electrical conduction system of the heart, causing it to contract.

Cardiac electrophysiology

Cardiac electrophysiology is a branch of cardiology and basic science focusing on the electrical activities of the heart. The term is usually used in clinical context, to describe studies of such phenomena by invasive (intracardiac) catheter recording of spontaneous activity as well as of cardiac responses to programmed electrical stimulation - clinical cardiac electrophysiology. However, cardiac electrophysiology also encompasses basic research and translational research components.

Closing (morphology)

In mathematical morphology, the closing of a set () A by a structuring element B is the erosion of the dilation of that set, where and denote the dilation and erosion, respectively. In , closing is, together with opening, the basic workhorse of morphological noise removal. Opening removes small objects, while closing removes small holes. It is idempotent, that is, . It is increasing, that is, if , then . It is extensive, i.e., . It is translation invariant.

Opening (morphology)

In mathematical morphology, opening is the dilation of the erosion of a set A by a structuring element B: where and denote erosion and dilation, respectively. Together with closing, the opening serves in computer vision and as a basic workhorse of morphological noise removal. Opening removes small objects from the foreground (usually taken as the bright pixels) of an image, placing them in the background, while closing removes small holes in the foreground, changing small islands of background into foreground.

Cardiac output

In cardiac physiology, cardiac output (CO), also known as heart output and often denoted by the symbols , , or , is the volumetric flow rate of the heart's pumping output: that is, the volume of blood being pumped by a single ventricle of the heart, per unit time (usually measured per minute). Cardiac output (CO) is the product of the heart rate (HR), i.e. the number of heartbeats per minute (bpm), and the stroke volume (SV), which is the volume of blood pumped from the left ventricle per beat; thus giving the formula: Values for cardiac output are usually denoted as L/min.

Structuring element

In mathematical morphology, a structuring element is a shape, used to probe or interact with a given image, with the purpose of drawing conclusions on how this shape fits or misses the shapes in the image. It is typically used in morphological operations, such as dilation, erosion, opening, and closing, as well as the hit-or-miss transform. According to Georges Matheron, knowledge about an object (e.g., an image) depends on the manner in which we probe (observe) it.

Wolff–Parkinson–White syndrome

Wolff–Parkinson–White syndrome (WPWS) is a disorder due to a specific type of problem with the electrical system of the heart involving an accessory pathway able to conduct electrical current between the atria and the ventricles, thus bypassing the atrioventricular node. About 60% of people with the electrical problem developed symptoms, which may include an abnormally fast heartbeat, palpitations, shortness of breath, lightheadedness, or syncope. Rarely, cardiac arrest may occur.

Atrium (heart)

The atrium (; : atria) is one of the two upper chambers in the heart that receives blood from the circulatory system. The blood in the atria is pumped into the heart ventricles through the atrioventricular mitral and tricuspid heart valves. There are two atria in the human heart – the left atrium receives blood from the pulmonary circulation, and the right atrium receives blood from the venae cavae of the systemic circulation. During the cardiac cycle the atria receive blood while relaxed in diastole, then contract in systole to move blood to the ventricles.

Tachycardia

Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate. In general, a resting heart rate over 100 beats per minute is accepted as tachycardia in adults. Heart rates above the resting rate may be normal (such as with exercise) or abnormal (such as with electrical problems within the heart). Tachycardia can lead to fainting. When the rate of blood flow becomes too rapid, or fast blood flow passes on damaged endothelium, it increases the friction within vessels resulting in turbulence and other disturbances.