Neural probe combining microelectrodes and a droplet-based microdialysis collection system for high temporal resolution sampling
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The physiological properties of cells are typically investigated in ensembles yielding averaged data that mask heterogeneities present in any cell population. Single-cell analysis techniques based on microfluidic "lab on a chip" (LOC) devices have recently ...
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2008
A time series of the hemispheric distribution of integrated water vapor measured with the ASMUWARA radiometer are analyzed by means of Empirical Orthogonal Functions (EOFs). The data were acquired in February 2007 at the Zimmerwald observatory in Switzerla ...
We propose a simple microfluidic device for protein preconcentration based on the electrokinetic trapping principle. It comprises a narrow Nafion strip that is simply cut from a commercial membrane and is integrated into a molded poly(dimethylsiloxane) (PD ...
American Chemical Society2010
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This paper reports on silicon-based microprobes, 8 mm long and 250 mu m x 250 mu m cross-section, comprising four recessed biosensor microelectrodes (50 mu m x 150 mu m) per probe shank coated with an enzymatic layer for the selective detection of choline ...
We might be at the turning point where research in microfluidics undertaken in academia and industrial research laboratories, and substantially sponsored by public grants, may provide a range of portable and networked diagnostic devices. In this Progress R ...
The application of electrical fields within a microfluidic channel enables many forms of manipulation necessary for lab-on-a-chip devices. Patterning electrodes inside the microfluidic channel generally requires multi-step optical lithography. Here, we uti ...
Royal Society of Chemistry2010
Abstract Microfluidics for most bio-related diagnostic applications typically requires single usage disposable chips to avoid bio-fouling and cross-contamination. Individual piece-wise manufacturing of polymeric microfluidic devices has been widely employe ...
With the growing importance of miniaturized energy applications and the development of micro Total Analysis Systems (μTAS), we have realized microfluidic devices, namely, magnetic micropumps, microfluidic fuel cells and membrane-based protein preconcentrat ...
Functional electrical stimulation (FES) is limited by the rapid onset of muscle fatigue caused by localized nerve excitation repeatedly activating only a subset of motor units. The purpose of this study was to investigate reducing fatigue by sequentially c ...