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Publication
Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
A hybrid microfluidic/electrochemical system is described for the time-resolved detection of dopamine (DA) from neuron-like PC12 cells cultured on a patch of filter paper. Cell adherence to the surface of the paper is investigated using fluorescence microscopy. DA release after stimulation with acetylcholine, in the presence or absence of drugs, is studied. Overall, the results obtained with this system are in good agreement with single cell data, thus demonstrating the validity of our approach for higher-throughput quantitative chemical analyses on tissue or organs-on-a-chip.
Suliana Manley, Martin Weigert, Chen Zhang, Willi Leopold Stepp, Dora Mahecic, Juliette Griffie
Suliana Manley, Jenny Sülzle, Laila Abdelaziz Abdelmoniem Elfeky