Atrial fibrillation septal pacing: translation of modelling results
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Repolarization Alternans and Atrial Remodeling Introduction Paroxysmal atrial fibrillation (AF) may be triggered by intermittent atrial tachycardia, and ultimately lead to persistent AF. However, the mechanisms by which intermittent atrial tachycardia prom ...
We analyse the haemodynamics of the left atrium, highlighting differences between healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-specific geometries of the left atria to simulate blood flow dyn ...
Ultrafast acoustoelectric imaging (UAI) is a novel method for the mapping of biological current densities, which may improve the diagnosis and monitoring of cardiac activation diseases such as arrhythmias. This paper evaluates the feasibility of performing ...
In the present model-based study, the correlation dimension (D2) was used as a measure of the effectiveness of atrial septal pacing during atrial fibrillation (AF). From ongoing simulated atrial fibrillation, instantaneous transmembrane potential maps were ...
The sensing of left ventricular (LV) activity is fundamental in the diagnosis and monitoring of cardiovascular health in high-risk patients after cardiac surgery to achieve better short- and long-term outcome. Conventional approaches rely on noninvasive me ...
Computer model-based simulations have shown that rapid stimulation at 60-100% of atrial fibrillation cycle length (AFCL) from a ring of electrodes located around the septum may induce local capture in both atria for most AF dynamics. The present study aims ...
The present study investigates the potential of the Largest Lyapunov Exponent (LLE) for the quantification of AF complexity as a marker of antitachycardia pacing (ATP) effectiveness in a biophysical model of the human atria. From ongoing simulated atrial f ...
Publishing House of the Slovak Academy of Sciences2014
Preliminary studies showed that the septum area was the only location allowing local capture of both the atria during rapid pacing of atrial fibrillation (AF) from a single site. The present model-based study investigated the influence of atrial substrate ...
Introduction: Moving to clinical validation is an essential phase with every model-based result. However, this translation is often not straightforward because animal models differ from human computer models in many anatomic and electrophysiologic ways, wh ...
Objectives: Rapid pacing of atrial fibrillation (AF) can induce local atrial capture. The present model-based study investigated the impact of atrial tissue conduction velocity on AF capture ability during rapid septal pacing. Methods: The AF model combine ...
