Publication

Atrial fibrillation septal pacing: translation of modelling results

Publications associées (32)

Implementation of an epicardial implantable MEMS sensor for continuous and real-time postoperative assessment of left ventricular activity in adult minipigs over a short- and long-term period

The sensing of left ventricular (LV) activity is fundamental in the diagnosis and monitoring of cardiovascular health in high-risk patients after cardiac surgery to achieve better short- and long-term outcome. Conventional approaches rely on noninvasive me ...

Aip Publishing2024

Impact of atrial fibrillation on left atrium haemodynamics: A computational fluid dynamics study

Alfio Quarteroni, Luca Dede'

We analyse the haemodynamics of the left atrium, highlighting differences between healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-specific geometries of the left atria to simulate blood flow dyn ...

PERGAMON-ELSEVIER SCIENCE LTD2022

Mapping Biological Current Densities With Ultrafast Acoustoelectric Imaging: Application to the Beating Rat Heart

Pierre-Marc Jean Marie Dansette

Ultrafast acoustoelectric imaging (UAI) is a novel method for the mapping of biological current densities, which may improve the diagnosis and monitoring of cardiac activation diseases such as arrhythmias. This paper evaluates the feasibility of performing ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2019

Experimental study of atrial fibrillation cycle length during rapid atrial septal pacing

Jean-Marc Vesin, Adrian Luca, Sasan Yazdani

Computer model-based simulations have shown that rapid stimulation at 60-100% of atrial fibrillation cycle length (AFCL) from a ring of electrodes located around the septum may induce local capture in both atria for most AF dynamics. The present study aims ...

2017

Experimental Testing of AF Septal Modeling Results

Adrian Luca

Introduction: Moving to clinical validation is an essential phase with every model-based result. However, this translation is often not straightforward because animal models differ from human computer models in many anatomic and electrophysiologic ways, wh ...

2016

Impact of Conduction Velocity on Local Capture of Atrial Fibrillation Induced by Rapid Pacing

Jean-Marc Vesin, Adrian Luca, Alexandru Rusu

Objectives: Rapid pacing of atrial fibrillation (AF) can induce local atrial capture. The present model-based study investigated the impact of atrial tissue conduction velocity on AF capture ability during rapid septal pacing. Methods: The AF model combine ...

2015

Correlation Dimension as a Measure of the Atrial Fibrillation Capture during Atrial Septal Pacing

Jean-Marc Vesin, Adrian Luca

In the present model-based study, the correlation dimension (D2) was used as a measure of the effectiveness of atrial septal pacing during atrial fibrillation (AF). From ongoing simulated atrial fibrillation, instantaneous transmembrane potential maps were ...

2014

Influence of atrial substrate on local capture induced by rapid pacing of atrial fibrillation

Jean-Marc Vesin, Vincent Jacquemet, Alexandru Rusu

Preliminary studies showed that the septum area was the only location allowing local capture of both the atria during rapid pacing of atrial fibrillation (AF) from a single site. The present model-based study investigated the influence of atrial substrate ...

Oxford University Press2014

Assessment of AF capture during antitachycardia pacing using largest Lyapunov exponent estimation. Insights from a biophysical model

Jean-Marc Vesin, Adrian Luca

The present study investigates the potential of the Largest Lyapunov Exponent (LLE) for the quantification of AF complexity as a marker of antitachycardia pacing (ATP) effectiveness in a biophysical model of the human atria. From ongoing simulated atrial f ...

Publishing House of the Slovak Academy of Sciences2014

Intermittent Atrial Tachycardia Promotes Repolarization Alternans and Conduction Slowing During Rapid Rates, and Increases Susceptibility to Atrial Fibrillation in a Free-Behaving Sheep Model

Jean-Marc Vesin, Florian Jousset, Etienne Pruvot

Repolarization Alternans and Atrial Remodeling Introduction Paroxysmal atrial fibrillation (AF) may be triggered by intermittent atrial tachycardia, and ultimately lead to persistent AF. However, the mechanisms by which intermittent atrial tachycardia prom ...

Wiley-Blackwell2014

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