Folding@homeFolding@home (FAH or F@h) is a distributed computing project aimed to help scientists develop new therapeutics for a variety of diseases by the means of simulating protein dynamics. This includes the process of protein folding and the movements of proteins, and is reliant on simulations run on volunteers' personal computers. Folding@home is currently based at the University of Pennsylvania and led by Greg Bowman, a former student of Vijay Pande.
Computational scienceComputational science, also known as scientific computing, technical computing or scientific computation (SC), is a division of science that uses advanced computing capabilities to understand and solve complex physical problems. This includes Algorithms (numerical and non-numerical): mathematical models, computational models, and computer simulations developed to solve sciences (e.
MOSFETThe metal-oxide-semiconductor field-effect transistor (MOSFET, MOS-FET, or MOS FET) is a type of field-effect transistor (FET), most commonly fabricated by the controlled oxidation of silicon. It has an insulated gate, the voltage of which determines the conductivity of the device. This ability to change conductivity with the amount of applied voltage can be used for amplifying or switching electronic signals. A metal-insulator-semiconductor field-effect transistor (MISFET) is a term almost synonymous with MOSFET.
Markov chain Monte CarloIn statistics, Markov chain Monte Carlo (MCMC) methods comprise a class of algorithms for sampling from a probability distribution. By constructing a Markov chain that has the desired distribution as its equilibrium distribution, one can obtain a sample of the desired distribution by recording states from the chain. The more steps that are included, the more closely the distribution of the sample matches the actual desired distribution. Various algorithms exist for constructing chains, including the Metropolis–Hastings algorithm.
Alfvén's theoremIn ideal magnetohydrodynamics, Alfvén's theorem, or the frozen-in flux theorem, states that electrically conducting fluids and embedded magnetic fields are constrained to move together in the limit of large magnetic Reynolds numbers. It is named after Hannes Alfvén, who put the idea forward in 1943. Alfvén's theorem implies that the magnetic topology of a fluid in the limit of a large magnetic Reynolds number cannot change. This approximation breaks down in current sheets, where magnetic reconnection can occur.
Geomagnetic reversalA geomagnetic reversal is a change in a planet's magnetic field such that the positions of magnetic north and magnetic south are interchanged (not to be confused with geographic north and geographic south). The Earth's field has alternated between periods of normal polarity, in which the predominant direction of the field was the same as the present direction, and reverse polarity, in which it was the opposite. These periods are called chrons. Reversal occurrences are statistically random.
Nuclear magnetic resonanceNuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are perturbed by a weak oscillating magnetic field (in the near field) and respond by producing an electromagnetic signal with a frequency characteristic of the magnetic field at the nucleus. This process occurs near resonance, when the oscillation frequency matches the intrinsic frequency of the nuclei, which depends on the strength of the static magnetic field, the chemical environment, and the magnetic properties of the isotope involved; in practical applications with static magnetic fields up to ca.
Geosynchronous orbitA geosynchronous orbit (sometimes abbreviated GSO) is an Earth-centered orbit with an orbital period that matches Earth's rotation on its axis, 23 hours, 56 minutes, and 4 seconds (one sidereal day). The synchronization of rotation and orbital period means that, for an observer on Earth's surface, an object in geosynchronous orbit returns to exactly the same position in the sky after a period of one sidereal day.
Generation III reactorGeneration III reactors, or Gen III reactors, are a class of nuclear reactors designed to succeed Generation II reactors, incorporating evolutionary improvements in design. These include improved fuel technology, higher thermal efficiency, significantly enhanced safety systems (including passive nuclear safety), and standardized designs intended to reduce maintenance and capital costs. They are promoted by the Generation IV International Forum (GIF).
Supermassive black holeA supermassive black hole (SMBH or sometimes SBH) is the largest type of black hole, with its mass being on the order of hundreds of thousands, or millions to billions of times the mass of the Sun (). Black holes are a class of astronomical objects that have undergone gravitational collapse, leaving behind spheroidal regions of space from which nothing can escape, not even light. Observational evidence indicates that almost every large galaxy has a supermassive black hole at its center.
